Celiac Plexus Neurolysis for Abdominal Cancer Pain: A Systematic Review

Celiac plexus neurolysis for the treatment of upper abdominal cancer pain

Optimal treatment of oncologic pain is a challenge to all professionals who deal with cancer and its complications. The management of upper abdominal pain is usually difficult and it is often refractory to conservative therapies. In this context, celiac plexus neurolysis (CPN) appears to be an important and indispensable tool because it alleviates pain, gives comfort to patients and is a safe p...

Celiac plexus neurolysis.

Pancreatic cancer is the tenth most common malignancy and the fourth cause of cancerrelated death in Western countries. Because 5year survival in referral centers is less than 30%, clinical management of most patients involves palliation of the symptoms of which 90% are weight loss, jaundice, and pain. While jaundice related to biliary obstruction can be palliated by means of endoscopic therapy...

EUS-guided celiac plexus neurolysis and celiac plexus block.

Pancreatic cancer and chronic pancreatitis commonly produce pain that is difficult to control.1,2 Initial therapy with nonsteroidal anti-inflammatory agents (NSAIDs) is often inadequate and necessitates opioid administration. Although opioids effectively relieve pain, they are associated with dry mouth, constipation, nausea, vomiting, drowsiness, delirium, and may impair immune function.3,4 In ...

EUS-guided celiac plexus block/neurolysis.

Pain palliation by endoscopic ultrasound-guided celiac plexus neurolysis in patients with unresectable pancreatic cancer.

BACKGROUND Endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) represents an alternative approach to pain palliation in patients with advanced pancreatic cancer. AIM to evaluate the safety and initial efficacy of EUS-CPN in patients with painful unresectable pancreatic cancer. METHODS Patients with inoperable body-tail pancreatic adenocarcinoma without prior chemotherapy and pai...